Standard Operating Procedures, Guidelines & Manuals for Safe Research

The following manuals may be required for your research operation, depending on what type of research you are performing, types of hazards, and engineering controls.  These documents are downloadable “Word” format so that you can print them for your operation as is, or download and modify them to meet your unique needs.

If you are working with chemicals, radioactive material or both, you will receive the applicable document binders to file your Standard Operating Procedures and compliance manuals along with inventories, training records, and other related safety and regulatory documents.

The time to complete each manual and binder depends on the factors to consider when projecting your research start date.  EHS can review these documents during the commissioning visit, or you may send them to EHS to be reviewed.  If you send the documents to EHS to be reviewed, it will take EHS a couple of days to provide feedback to you.

  • Infectious Agents
  • Recombinant DNA
  • Select Agents
  • Animal tissue, fluids, and cells (Known or suspected of being infectious
Biosafety Manual
  • Human derived tissues, fluid, and cells
Exposure Control Plan
  • Biological toxins
  • Potentially hazardous chemicals or drugs

NOTE: Hazardous chemicals, include FDA approved or experimental pharmaceutical products, laboratory chemicals and inhalation anesthetics to live animals.

The Chemical Hygiene Plan Document Binder


  • EHS, Research Health and Safety provides this pre-assembled binder to lab directors.  The lab directors MUST complete the forms in the binder and maintain the records in the binder
  • Refer to the Chemical Hygiene Plan for instructions to complete the required documents in the Chemical Hygiene Plan Document Binder.
  • Radioactive materials
Radiation Safety Manual and Records Binder

NOTE: RSS provides this pre-assembled binder to the authorized user.  Authorized users must add their authorization approval letter and maintain the records in the binder

Standard Operating Procedures

Standard Operating Procedures for many of the commonly used chemicals and equipment necessary for research.  NOTE: We understand the nature of research is exploration of new materials and novel methods, and you may need to develop SOPs that are not yet available on the website.  As a research partner we would like to expand our SOP library to assist others, and if you have an SOP that is not on the website, we are happy to post it for others to use.


Guidelines written by EHS is another resource to use when collecting and preparing documents for the manuals and binders.  The Guidelines Web page is organized by alphabetical order by topic. Some of the important guidelines to be aware of include: